Acomplia (Rimnobant)
Rimonabant (Acomplia) is used in the treatment of obesity and related conditions by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle. It switches off the same brain circuits that make people hungry when they smoke cannabis. Acomplia has also been shown to help in smoking cessation.
Rimonabant Dosage:
Use Rimonabant as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Rimonabant usage is one 20 mg tablet every day.
Ask your health care provider any questions you may have about how to use Acomplia.
Storage — How to store Rimonabant:
- Keep out of the reach of children.
- Store away from heat and direct light.
- Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
- Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.
Side effect of Rimnobant:
Side effects in the trial on Acomplia in obesity were vomiting and nausea, forcing about 19 percent of patients to leave the trial versus 13 percent of those who took placebo.
Clinical studies found that 26 percent of people taking Acomplia reported psychiatric symptoms, including anxiety, insomnia, panic attacks as well as increases in aggression and agitation compared to patients given a placebo.
Acomplia has also been shown to cause increased suicidal tendencies and other depressive symptoms. Shortly after market introduction, press reports and independent studies suggest that side-effects occur stronger and more commonly than shown by the manufacturer in their clinical studies. Reports of severe depression are frequent. This is deemed to result from the Acomplia's being active in the central nervous system, an area of human physiology so complex that the effects of a drug are extremely difficult to predict or anticipate.